ʻŌpala pā moʻomeheu kelepona 96-lua

ʻŌpala pā moʻomeheu kelepona 96-lua

ʻEnekinia Pololei no nā ʻEpekema Ola: ʻAnisika Ka ʻIke o ka ʻEnehana i ka Hoʻoheheʻe ʻana i nā Papa 96-Well

Mai ka Hoʻolālā Lab a i ka Hana Nui: Ka Huakaʻi o kahi Marvel Maʻamau

I loko o ke ao koʻikoʻi o ka noiʻi lāʻau lapaʻau a me ka biotechnology, ʻo ka wikiwiki a me ka hilinaʻi ka mea nui loa. Ma ka puʻuwai o nā ʻōnaehana nānā kiʻekiʻe he nui ʻole—nā lio hana automated e hoʻāʻo ana i nā tausani o nā moho lāʻau—aia kahi ʻāpana plastik maʻalahi hoʻopunipuni: ka papa moʻomeheu cell 96-well. No nā makahiki he ʻumi, ʻo kēia kahua maʻamau, me kona kapuaʻi waho o 127.76 x 85.48 mm, ʻo ia ke kāwele honua no nā hoʻokolohua olaola a me nā kemika.

Eia nō naʻe, he hana ʻenekinia paʻakikī kupaianaha ka hana ʻana i kēia mau papa. Pono ia i kahi hui kūlike o ka pololei micro-scale, ka maopopo optical, a me ke kūlike piha e hōʻoia i ka loaʻa ʻana o kahi cell e ulu ana i loko o kahi lab ma Boston i nā kūlana like me kekahi ma Berlin. Ke koi nei nā alakaʻi ʻoihana no ka miniaturization i nā lua 384 a hiki i 1536, hoʻonui ʻia nā pilikia loea, e koi ana i ka hāʻule ʻana o ka mānoanoa o ka paia i 0.5 mm a i ʻole ka liʻiliʻi. No Ansix Tech, he loea i ka hoʻoheheʻe ʻana i ka injection kiʻekiʻe, ʻo ka lanakila ʻana i kēia mau pilikia ʻaʻole ia he hana hana wale nō - he kūpaʻa ia e hoʻolalelale i ka ʻike ʻepekema honua.

Ke Kumu: Hoʻolālā a me ke Hana Hoʻohālike i Hoʻokele ʻia e ka Precision

Hoʻomaka ka hana ʻana o kahi ʻōmole papa 96-lua hilinaʻi ma mua loa o ka ʻoki ʻia ʻana o ke kila. Ma Ansix Tech, ua hoʻopaʻa ʻia ke kaʻina hana ma Design for Manufacturability (DFM), kahi ʻano akeakamai e hoʻopili ai i ka hakahaka ma waena o ka hoʻolālā kūpono a me ka hana hiki ke hana ʻia a kūpono hoʻi ke kumukūʻai.

Hoʻolālā mua a me ka Hoʻohālikelike: Hoʻomaka nā ʻenekinia me nā ana hana koʻikoʻi o ka pā: ka hohonu o ka lua, ka pālahalaha o lalo no ka microscopy kūlike, a me ka mamao pololei o ke kikowaena 9 mm e hōʻoiaʻiʻo ana i ka kūlike me nā mea lawelawe wai automated. Ma ka hoʻohana ʻana i nā polokalamu hoʻohālikelike holomua, hana lākou i ka nānā ʻana i ke kahe ʻana o ka mold e wānana pehea e hoʻopiha ai ka plastic heheʻe i nā lua paʻakikī 96 o ka mold. He mea koʻikoʻi kēia hoʻāʻo virtual no ka ʻike ʻana i nā hemahema hiki ke like me nā pahele ea, nā laina weld (hiki ke hoʻonāwaliwali i ke ʻano), a i ʻole ka hoʻopiha ʻole ʻia e hiki ai ke hoʻopilikia.

Hoʻohālikelike a me ka Hōʻoia: A laila hana ʻia kahi prototype kino, me ka hoʻohana pinepine ʻana i nā ʻano hana wikiwiki. ʻO kēia pae no ka ʻoi aku ma mua o ka nānā maka wale nō. Hana nā ʻenekinia i nā hoʻokolohua hōʻoia koʻikoʻi: ke ana ʻana i nā ʻae ʻana o ka dimensional i mālama pinepine ʻia i loko o ± 0.1 mm, e nānā ana i ke kūlike maikaʻi-a-maikaʻi, a me ka hōʻoia ʻana i nā waiwai optical o ka lalo o ka pā. Hoʻihoʻi ʻia kēia ʻikepili empirical e hoʻomaʻemaʻe i ke kumu hoʻohālike kikohoʻe, e hōʻoia ana i ka hope loa. Hoʻolālā Mold he paʻa.

Ka Puʻuwai o ka Mea: ʻŌmole holomua Hoʻolālā a me ka Hana ʻana

Me kahi hoʻolālā i hōʻoia ʻia, neʻe ka manaʻo i ka hana ʻana i ka ʻōmole ponoʻī—he mea hana pololei loa e wehewehe ana i ka maikaʻi o ka ʻāpana a me ka hoʻokele waiwai o ka papahana.

Koho ʻana i ke kila kila: He mea koʻikoʻi ke koho ʻana i ke kila no ke ola lōʻihi a me ka pololei. No nā papa 96-well, hoʻohana pinepine ʻo Ansix Tech i nā kila paʻakikī, kūpaʻa i ka pala e like me S136 a i ʻole DIN 1.2344. Kūʻē kēia mau mea kiʻekiʻe i ka ʻaʻahu ʻana mai nā plastics abrasive a kū i ke kaʻapuni wela mau o ka hoʻoheheʻe ʻana i ka injection, e hōʻoiaʻiʻo ana e hana ka ʻōpala i nā ʻumi tausani o nā papa me ka ʻole o ka hōʻino ʻana i ka maikaʻi.

Hoʻolālā ʻōnaehana koʻikoʻi: He hana noʻeau o ka micro-engineering ka loko o ka mold. Pono e hoʻolālā pono ʻia ka ʻōnaehana gating—nā kahawai e komo ai ka plastic i loko o nā lua. Hoʻohana pinepine ʻia nā ʻōnaehana holo wela e hoʻopau i ka ʻōpala a hōʻoia i ke kahe mau ʻana o nā mea i kēlā me kēia lua. Hoʻohana ka ʻōnaehana ejection i nā ʻumi o nā pine i kau pono ʻia e paʻi mālie akā paʻa i ka papa palupalu mai ka mold me ka ʻole o ka hoʻoulu ʻana i nā māka koʻikoʻi a i ʻole ke ʻano ʻē.

ʻO ka Hoʻololi Hoʻoluʻu: ʻO ka mea hou koʻikoʻi paha ka hoʻoluʻu ʻana. ʻO nā kahawai wili laina pololei kuʻuna e alakaʻi pinepine ai i ka hoʻoluʻu ʻole ʻia, e hana ana i ka warpage a me ka hoʻolōʻihi ʻana i nā manawa pōʻaiapuni. Hoʻohana ʻo Ansix Tech i nā kahawai hoʻoluʻu conformal i paʻi ʻia i ka 3D. Hiki i kēia mau kahawai, i hana ʻia me ka hoʻohana ʻana i ka Direct Metal Laser Sintering (DMLS), ke nalo a me ke contour kūpono a puni ke ʻano o kēlā me kēia lua, e hahai ana i ke ʻano o ka mold ma kahi mamao mau.

Hopena: Hiki i kēia ʻenehana ke hoʻokaʻawale wikiwiki a like i ka wela. Ma ka mālama ʻana i ka mahana kūpono o ka ʻōpala, hoʻemi nui ia i ka manawa hoʻoluʻu o ka ʻāpana—ʻo ia ka manawa lōʻihi loa i loko o ke kaʻina hana injection. Hōʻike nā hihia mai ka ʻoihana e hiki i kēlā hoʻoluʻu holomua ke hōʻemi i nā manawa kaʻina hana ma mua o 25%, e unuhi pololei ana i ka hana kiʻekiʻe aʻe a me ke kumukūʻai haʻahaʻa no kēlā me kēia ʻāpana.

Ke Aʻo ʻana i ke Kaʻina Hana: Mai ka ʻEpekema Mea a i ka Hōʻoiaʻiʻo Kūlana

Me ka ʻōmole kūpono, ʻo ka pilikia hope loa, ʻo ia ka hoʻokō ʻana i ke kaʻina hana hoʻoheheʻe inikini me ke kūlike mau.

ʻEpekema Mea Hana: ʻO ka polystyrene (PS) ka mea maʻamau o ka ʻoihana. I kona kūlana maʻemaʻe, he hydrophobic ka PS, akā no ka moʻomeheu cell, ʻo ka hapa nui o nā papa e hana ʻia i kahi mālama ʻili (e like me ka plasma kinoea) e hana iā lākou i hydrophilic a kūpono i ka hoʻopili ʻana o nā cell. Hana pū ʻo Ansix Tech me nā mea hoʻolako resin e koho i nā māka PS kikoʻī e hāʻawi ana i ke kaulike maikaʻi loa o ka maopopo, ka ikaika, a me nā ʻano kahe no ka hoʻoheheʻe ʻana i ka paia lahilahi. Hiki ke hoʻokomo ʻia nā mea hoʻohui no nā pono kikoʻī, e like me ka pigmentation ʻeleʻele no nā hoʻāʻo fluorescence a i ʻole nā ​​māka UV-transmissive no nā noi kūikawā.

Hoʻonui a me ka Mana o ke Kaʻina Hana: Hoʻomalu ʻia ke kaʻina hana hoʻoheheʻe ʻia e nā ʻumi o nā palena i hoʻopili ʻia: ka mahana hoʻoheheʻe, ka wikiwiki a me ke kaomi o ka injection, ke kaomi hoʻopili, a me ka manawa hoʻomaʻalili. Hoʻohana ʻo Ansix Tech i nā loina hoʻoheheʻe ʻepekema a me nā algorithms optimization multi-objective e ʻike i ka meaʻai kūpono. Hoʻohālikelike kēia mau algorithms i nā pahuhopu hoʻokūkū—e hoʻemi ana i ka manawa pōʻaiapuni, e hoʻemi ana i ka hoʻohana ʻana i nā mea, a me ka hoʻonui ʻana i ka maikaʻi—e ʻike i ka hoʻonohonoho hana holoʻokoʻa kūpono loa.

Ka Hōʻoiaʻiʻo Kūlana Mau Loa: ʻAʻole hiki ke kūkākūkā ʻia ke kūlana maikaʻi i nā ʻepekema ola. Nānā ʻia kēlā me kēia holo hana ma o ka Statistical Process Control (SPC), e nānā ana i nā ana koʻikoʻi i ka manawa maoli. Hana ʻia nā nānā ʻana i nā papa i hoʻopau ʻia no nā hemahema ʻike maka, akā no nā waiwai hana hoʻi. He mea nui ka pālahalaha e pale ai i ka neʻe ʻana o ka wai ma waena o nā luawai, a ua hōʻoia ʻia ka maopopo o ka ʻike. ʻO ke koʻikoʻi, ua hoʻopili ʻia nā papa i manaʻo ʻia no ka hana olaola koʻikoʻi i loko o nā wahi lumi maʻemaʻe e hōʻoia i ka sterile a me ka ʻole o nā pyrogens a i ʻole DNases e hiki ke hōʻino i nā hoʻokolohua.

Ke Hāʻawi nei i ka Waiwai: ʻO ka Hoʻohiki ʻenehana Ansix i ka Hui Pū ʻana

Ua unuhi ʻia ka ʻike loea o Ansix Tech i nā pono pololei a hiki ke ʻike ʻia no kāna mau mea kūʻai aku ma nā ʻāpana diagnostic a me biotech.

Hoʻemi Kumukūʻai ma o ka Pono Holoʻokoʻa: ʻO ke ʻano mālama kālā o ka hui he holoʻokoʻa. Hoʻomaka ia me ka hoʻonui ʻana i nā mea, e hōʻoiaʻiʻo ana ʻaʻohe hana nui. Hoʻomaopopo ʻia ia ma o ka hoʻonui ʻana i ke kaʻina hana e ʻomi ana i nā kekona mai kēlā me kēia pōʻaiapuni, e hoʻonui ana i ka hana. Hoʻopaʻa ʻia e ka holomua mua i ka hoʻolālā ʻana i ka mold, e hoʻopau ana i ka hana hou ʻana i ka mold pipiʻi a me ka manawa. ʻAe kēia pono i hoʻohui ʻia iā Ansix Tech e hoʻohaʻahaʻa nui i ke kumukūʻai o nā ʻāpana me ka ʻole o ka hoʻopilikia ʻana i nā kūlana kikoʻī e pono ai ka ʻoihana.

Ka wikiwiki a me ka hilinaʻi: Ma ka hoʻomaopopo ʻana he mea koʻikoʻi ka manawa-i-ka-mākeke i ka noiʻi, ua hoʻomaʻamaʻa ʻo Ansix Tech i kāna kaʻina hana mai ka hoʻolālā a i ka lawe ʻana. Ma ka hoʻokele ʻana i ke kaulahao holoʻokoʻa a me ka hoʻohana ʻana i nā ʻenehana e like me ka hoʻoluʻu conformal a me ka simulation digital, hōʻoia lākou ʻaʻole wale ka prototyping wikiwiki akā ʻo ka wānana, scalable, a me ka hana nui wikiwiki.

ʻO ka papa 96-well kahi mea e hiki ai ke hoʻohana i ka lāʻau lapaʻau hou. Ma hope o kona ʻano polystyrene maʻalahi he honua o ka ʻenekinia holomua, ka ʻepekema mea, a me ka hana pololei. Ma ka hoʻokele ʻana i kēia paʻakikī, hana ʻo Ansix Tech ma mua o ka hana ʻana i nā mea hoʻopau plastik; hāʻawi ia i kahi kahua hilinaʻi e hiki ai i nā mea noiʻi ke kūkulu i ka holomua hou, me ka hilinaʻi ua hana ʻia ka papa e paʻa ana i kā lākou ʻike i ka hemolele.

ʻO Ansix Tech Co Ltd

Inā he mau hoʻolālā kāu e pili ana i ka ʻōmole papa moʻomeheu cell 96-well, hiki iā ʻoe ke hoʻokaʻaʻike mai iā mākou i kēlā me kēia manawa. E hoʻolilo mākou i kou mau manaʻo i mea maoli, e hoʻokō i kāu mau moeʻuhane, a loaʻa nā kauoha nui mai ka mākeke. ʻO kā mākou ʻike pili ʻo info@ansixtech.com. A i ʻole e kelepona i kā mākou CTO, leka uila: stephen@ansixtech.com

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